All Pet Purrfection Inc. – Pediatric Health Tabs

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Pet Purrfection Inc. – Pediatric Health Tabs – 60 tabs

Unlike many pharmaceuticals, All Pet Purrfection’s supplements are formulated with high quality natural extracts designed to maximise efficacy and minimise side effects often associated with today’s chemical supplementation.

The growing recognition of both preventive and therapeutic values of natural dietary ingredients in family medicine is now available in veterinary medicine. Many pet health conditions, particularly those associated with aging, injury or disease, can often be greatly improved and optimal health may be achieved with a properly supplemented diet.

All our ingredients are purchased from reputable source. We mix, encapsulate and bottle these formulae in our own facility under very strict food safety and quality regulations. We also have the final product tested at an independent laboratory for active ingredients prior to shipment to our Clients.

Introduction

The health of a young animal is vital to its growth, development, and well-being, not just in its youth, but throughout its entire life.  It is therefore crucial that the young animal’s health is protected.

Unfortunately, young animals are very vulnerable to infection and disease caused by pathogenic organisms that enter the gastrointestinal tract.  Bacteria, viruses, and fungi are able to gain a foothold in the gastrointestinal (G.I.) tract of young animals because their immune systems are not yet fully developed.  Once a pathogen establishes a presence in the G.I. tract of a young animal, it is difficult for the immature immune system to successfully defend the body from infection and disease.

The effects of disease are also more severe for young animals than they are for mature animals.  Many pathogens that invade the G.I. tract damage the epithelial cells that line the tract and are responsible for absorbing the nutrients that the animal needs for its growth and development.  More importantly, the bodies of young animals are simply unable to absorb the damaging effects of disease, with the result that young animals are more likely to suffer serious or fatal harm.

The Pediatric Health Tabs are designed to assist the immune system of vulnerable young pets in the fight against invading pathogenic organisms.  Based on human products, these tabs contain Synermune™ Colostrum, proven through scientific trial and traditional use to be an effective, natural way to boost and enhance the immune system.

Colostrum
Colostrum is a specialized pre-milk secretion of the mammary gland.  It is produced by all mammals during the last weeks of pregnancy, and is the first food available to the newborn. Its most important function in nature is to boost and stimulate the immune system.  Colostrum is an incredible source of immunoglobulins, nutrients, vitamins and minerals, nucleotides, immunoenhancing molecules and growth-stimulating factors, and is vital to the newborn’s health, nutrition, and development.  Colostrum has been called ‘White Gold’ because of its critical role in maintaining and enhancing the health and immunity of vulnerable newborns. 

All newborn mammals will receive colostrum from their mother if they are able to feed within the first 24-48 hours after birth.  This colostrum boosts and stimulates the immune system of the newborn, protecting it from disease.  Unfortunately, the mother cannot afford to provide this extremely rich product for the extent of the animal’s vulnerable youth. 

Animals of all ages can now continue to benefit from the consumption of colostrum.  Bovine colostrum, which is very rich in immune-enhancing factors, is available as a potent immune-enhancing supplement.  The structures of the immunoglobulins, nutrients, immunoenhancing molecules and growth factors in bovine colostrum are nearly identical to those found in the colostrum of other mammals.  These molecules are, therefore, able to function very effectively in the bodies of animals of other species.  The benefits of supplementation with bovine colostrum have been proven in studies published in peer-reviewed biomedical journals.

Components of Colostrum
Colostrum is an extremely rich source of Immunoglobulins (Ig).  Immunoglobulins are protein molecules that are able to bind to pathogens such as bacteria, viruses and parasites, and are a vital constituent of the immune system.  The immunoglobulins from colostrum agglutinate (clump) bacteria, viruses, and parasites that enter the intestine – the site of infection for the vast majority of disease – facilitating their removal before they cause disease.  Immunoglobulins also decrease infection and disease by preventing pathogens from binding to intestinal surfaces.  Many pathogens must bind to surface receptors on intestinal cells before colonization and infection can occur, and so prevention of binding by immunoglobulins reduces the incidence of infection. 

The concentration of immunoglobulins in bovine colostrum is up to 240 times that of milk.  The main form of Ig in colostrum, known as IgG, normally accounts for 15% of the total weight of colostrum.  Synermune™ colostrum has been concentrated so that the immunoglobulins account for up to 25% of dry weight, increasing its ability to enhance immunity.

Many pathogenic bacteria require the presence of free iron molecules in the gut in order to grow and reproduce at a high rate.  The iron-binding glycoproteins Lactoferrin and Transferrin found in colostrum slow pathogen growth by sequestering free iron molecules in the gut and moving the iron into the bloodstream.  Slowing pathogen growth allows more time for the body to clear the pathogen, and therefore decreases the chance of infection.  Lactoferrin also attacks pathogens directly by destabilizing the coat membranes of gram-negative bacteria, which allows the body to attack them more successfully.  It has been shown that lactoferrin increases the ability of neutrophils, cellular components of the immune system, to attack and destroy bacterial invaders.  Lactoferrin has recently been proven to exhibit anti-viral properties against several different viruses, most likely by attaching to the virus and preventing it from entering the body’s cells.  Recent research has indicated that lactoferrin may bind to receptors in the intestine and act as a signal to stimulate the immune system.

Colostrum contains other constituents with antibacterial and antiviral properties;  A) Oligosaccharides and Glycoproteins compete with pathogenic bacteria for binding sites on the intestinal epithelium.  As described above, pathogens attach to binding sites in the intestine prior to colonization and infection.  Competition for these binding sites results in fewer opportunities for pathogenic attachment, colonization, and infection.  B) The enzymes Lysozyme and Peroxidase aggressively attack and destroy the cell walls of pathogenic bacteria, and the protein coat of some viruses.  C) Also present in colostrum is a Proline-Rich Polypeptide (PRP), which is known to have immunoregulatory properties.  It enhances those immune systems which exhibit low responsiveness, and helps to suppress hyperactivated immune systems.  PRP also stimulates the production of a class of glycoproteins known as Interferons.  These molecules act as a signal to healthy cells that a virus is present, and result in the development of anti-viral proteins and virus resistance.  For instance, interferon increases the activity of the enzyme Nitric Oxide Synthase, which produces a substance, nitric oxide, that destroys viruses.  D) The Cytokines IL-1, IL-2 and IL-6, present in colostrum, are also fundamental components of the immune system.  They have been shown to enhance B- and T-cell maturation and to increase the level of endogenous antibody production.  They are required to fight systemic infections and to protect against septic shock.  E) Colostrum contains a family of oligoribonucleopeptides known as Transfer Factors.  These molecules are able to ‘educate’ T-cells to function more effectively against specific antigens.  Like the other components of bovine colostrum, Transfer Factors do not act in a species-specific manner, and Transfer Factors from bovine colostrum are able to act on lymphocytes of other mammalian species.

Colostrum contains a number of growth and maturation factors.  Insulin, Somatomedins (IGF-1 and IGF-2), Somatotropin, Fibroblast Growth Factor (FGF), Transforming Growth Factors A and B (TGF-A and TGF-B), Platelet-Derived Growth Factor (PDGF), and Epithelial Growth Factor (EGF) form a powerful combination.  These naturally occurring substances have been shown in numerous clinical studies to enhance the synthesis of DNA, RNA and protein, while at the same time they inhibit the breakdown of protein.  There are receptors for these compounds throughout the intestinal tract, and they are postulated to be mediators of intestinal growth and development.   They are known to increase the epithelial cell mass of the intestine, influence the composition of absorptive surfaces, and may be involved in stimulating wound healing.  Maturation and proliferation of intestinal cells results in increased absorption of electrolytes and nutrients from the intestine.  These growth factors may also aid in resistance to disease, as pathogens are more likely to attack and infect immature or damaged intestinal cells.  IGF-1 is known to have strong anabolic effects on muscle tissue, as it is able to mimic most of the actions of Growth Hormone.  Supplementation with bovine colostrum has been shown in a recent scientific study to raise the serum level of IGF-1, although it has not been determined if the increased serum level is caused by absorption of colostral IGF-1 or by stimulation of endogenous production.

Use of Bovine Colostrum on Young Animals
The use of colostrum in veterinary medicine has generally been restricted to newborns. More recently, many controlled, scientific trials have proven that oral supplementation with bovine colostrum enhances immunity and provides protection from a variety of diseases for older animals.

Major pathogens that have been effectively treated with colostrum include rotavirus, Campylobacter jejuni, Cryptosporidium parvum, Staphylococcus aureus, Candida, and enterotoxigenic Escherichia coli.  Many animals commonly suffer from diarrhea caused by rotavirus infection, and treatment with colostrum has been shown to reduce the incidence and severity of diarrhea caused by this common virus.  Campylobacter, Cryptosporidium, and E. coli are the most common intestinal pathogens, causing disease in millions of people and animals each year.  In healthy individuals they generally cause self-limiting diarrhea, but in immunocompromised animals (due to illness or stress) these infections may be life-threatening.  Colostrum has been shown in several scientific studies published in the biomedical literature to reduce the incidence and severity of infection and diarrhea caused by these pathogens. 

Scientific study of bovine colostrum’s effects on the pathogenesis of disease in  adults is relatively young.  To date only the most common pathogens have been studied, but it is expected that continuing trials will identify other specific pathogens against which colostrum provides protection. 

The Synermune™ colostrum in the Pediatric Health Tabs enhances the local immunity in the gastrointestinal tract, the main site of pathogenic infection.  It has been proven in controlled scientific studies to decrease the risk and severity of infection due to bacterial, parasitic, and viral pathogens.

Synermune™ Colostrum

To ensure maximum potency, the Pediatric Health Tabs contain only Synermune™ Colostrum.  This colostrum is collected only from the first milking of USDA Grade A cows after the second calving.  This practice ensures that the immunoenhancing components of colostrum are at peak concentration.  Cows must be certified to be free from antibiotic treatment at the time of milking.  Inspection and testing ensures that the colostrum is free of pesticides, antibiotics, and anabolic hormones.  The colostrum is not subjected to excessive heat during the manufacturing process, and so the immunoenhancing properties are retained.  The needs of the calves are met first, and so there is no cruelty to animals involved in the collection process.

Conclusion
The Pediatric Health Tabs are designed to boost and enhance the immune system of young pets.  They are based on the use of Synermune™ bovine colostrum, which has been proven in studies published in the biomedical literature to be effective against a wide variety of pathogenic organisms.  The protection of the vulnerable young pet should help the pet enjoy a healthier, happier life.

Gastrointestinal (G.I.) health is crucial to the full and complete development of animals. Bacterial and viral colonization can damage the cells of the intestines and decrease the assimilation of nutrients in feed. Decreased assimilation leads to lower daily weight gain, a condition from which your pet may never fully recover.

Health Tabs for Puppies and Kittens allow for optimal development into adulthood by enhancing the local immune system of the G.I. tract. This can substantially reduce the frequency of illnesses which a young pet may experience.

Ingredients:
Pure colostrums, infant probiotic blend, dextrose, flavour.

 

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